Shedding of glycan-modifying enzymes by signal peptide peptidase-like 3 (SPPL3) regulates cellular N-glycosylation

Protein N-glycosylation is involved in a variety of physiological and pathophysiological processes such as autoimmunity, tumour progression and metastasis. Signal peptide peptidase-like 3 (SPPL3) is an intramembrane-cleaving aspartyl protease of the GxGD type. Its physiological function, however, ha...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Voss, Matthias, Künzel, Ulrike, Higel, Fabian, Kuhn, Peer-Hendrik, Colombo, Alessio, Fukumori, Akio, Haug-Kröper, Martina, Klier, Bärbel, Grammer, Gudula, Seidl, Andreas, Schröder, Bernd, Obst, Reinhard, Steiner, Harald, Lichtenthaler, Stefan F, Haass, Christian, Fluhrer, Regina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Publishing Ltd 2014
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282638/
https://ncbi.nlm.nih.gov/pubmed/25354954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488375
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