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Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery

Intrinsic tumor resistance to radiotherapy limits the efficacy of ionizing radiation (IR). Sensitizing cancer cells specifically to IR would improve tumor control and decrease normal tissue toxicity. The development of tumor targeting technologies allows for developing potent radiosensitizing drugs....

詳細記述

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書誌詳細
出版年:Cancer Res
主要な著者: Buckel, Lisa, Savariar, Elamprakash N., Crisp, Jessica L., Jones, Karra A., Hicks, Angel M., Scanderbeg, Daniel J., Nguyen, Quyen T., Sicklick, Jason K., Lowy, Andrew M., Tsien, Roger Y., Advani, Sunil J.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458508/
https://ncbi.nlm.nih.gov/pubmed/25681274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1931
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