Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery

Intrinsic tumor resistance to radiotherapy limits the efficacy of ionizing radiation (IR). Sensitizing cancer cells specifically to IR would improve tumor control and decrease normal tissue toxicity. The development of tumor targeting technologies allows for developing potent radiosensitizing drugs....

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Buckel, Lisa, Savariar, Elamprakash N., Crisp, Jessica L., Jones, Karra A., Hicks, Angel M., Scanderbeg, Daniel J., Nguyen, Quyen T., Sicklick, Jason K., Lowy, Andrew M., Tsien, Roger Y., Advani, Sunil J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458508/
https://ncbi.nlm.nih.gov/pubmed/25681274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1931
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