Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery

Intrinsic tumor resistance to radiotherapy limits the efficacy of ionizing radiation (IR). Sensitizing cancer cells specifically to IR would improve tumor control and decrease normal tissue toxicity. The development of tumor targeting technologies allows for developing potent radiosensitizing drugs....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Res
Prif Awduron: Buckel, Lisa, Savariar, Elamprakash N., Crisp, Jessica L., Jones, Karra A., Hicks, Angel M., Scanderbeg, Daniel J., Nguyen, Quyen T., Sicklick, Jason K., Lowy, Andrew M., Tsien, Roger Y., Advani, Sunil J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458508/
https://ncbi.nlm.nih.gov/pubmed/25681274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1931
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