Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery

Intrinsic tumor resistance to radiotherapy limits the efficacy of ionizing radiation (IR). Sensitizing cancer cells specifically to IR would improve tumor control and decrease normal tissue toxicity. The development of tumor targeting technologies allows for developing potent radiosensitizing drugs....

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Buckel, Lisa, Savariar, Elamprakash N., Crisp, Jessica L., Jones, Karra A., Hicks, Angel M., Scanderbeg, Daniel J., Nguyen, Quyen T., Sicklick, Jason K., Lowy, Andrew M., Tsien, Roger Y., Advani, Sunil J.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458508/
https://ncbi.nlm.nih.gov/pubmed/25681274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1931
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