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Method for trapping affinity chromatography of transcription factors using aldehyde-hydrazide coupling to agarose

The uses of a method of coupling DNA is investigated for trapping and purifying transcription factors. Using the GFP-C/EBP fusion protein as a model, trapping gives higher purity and comparable yield to conventional affinity chromatography. The chemistry utilized is mild and was shown to have no det...

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Detalhes bibliográficos
Publicado no:Anal Biochem
Main Authors: Jia, Yinshan, Jarrett, Harry W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458446/
https://ncbi.nlm.nih.gov/pubmed/25935261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2015.04.025
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