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CXCR4 Blockade Attenuates Hyperoxia Induced Lung Injury in Neonatal Rats
BACKGROUND: Lung inflammation is a key factor in the pathogenesis of bronchopulmonary dysplasia (BPD). Stromal derived factor-1 (SDF-1) and its receptor chemokine receptor 4 (CXCR4) modulate the inflammatory response. Whether antagonism of CXCR4 will alleviate lung inflammation in neonatal hyperoxia...
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| Publicado en: | Neonatology |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4458217/ https://ncbi.nlm.nih.gov/pubmed/25825119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000371835 |
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