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INHIBITION OF THE SDF-1/CXCR4 AXIS ATTENUATES NEONATAL HYPOXIA-INDUCED PULMONARY HYPERTENSION

Exposure of the neonatal lung to chronic hypoxia produces significant pulmonary vascular remodeling, right ventricular hypertrophy (RVH), and decreased lung alveolarization. Given recent data suggesting that stem cells could contribute to pulmonary vascular remodeling and RVH, we tested the hypothes...

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Detalhes bibliográficos
Main Authors: Young, Karen C, Torres, Eneida, Hatzistergos, Konstantinos E., Hehre, Dorothy, Suguihara, Cleide, Hare, Joshua M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757744/
https://ncbi.nlm.nih.gov/pubmed/19423843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.197533
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