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INHIBITION OF THE SDF-1/CXCR4 AXIS ATTENUATES NEONATAL HYPOXIA-INDUCED PULMONARY HYPERTENSION

Exposure of the neonatal lung to chronic hypoxia produces significant pulmonary vascular remodeling, right ventricular hypertrophy (RVH), and decreased lung alveolarization. Given recent data suggesting that stem cells could contribute to pulmonary vascular remodeling and RVH, we tested the hypothes...

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Bibliografiske detaljer
Main Authors: Young, Karen C, Torres, Eneida, Hatzistergos, Konstantinos E., Hehre, Dorothy, Suguihara, Cleide, Hare, Joshua M.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757744/
https://ncbi.nlm.nih.gov/pubmed/19423843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.197533
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