An Apela RNA-Containing Negative Feedback Loop Regulates p53-Mediated Apoptosis in Embryonic Stem Cells

Maintaining genomic integrity is of paramount importance to embryonic stem cells (ESCs), as mutations are readily propagated to daughter cells. ESCs display hypersensitivity to DNA damage-induced apoptosis (DIA) to prevent such propagation, although the molecular mechanisms underlying this apoptotic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Stem Cell
Prif Awduron: Li, Mangmang, Gou, Hongfeng, Tripathi, Brajendra K., Huang, Jing, Jiang, Shunlin, Dubois, Wendy, Waybright, Tim, Lei, Ming, Shi, Jianxin, Zhou, Ming
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458197/
https://ncbi.nlm.nih.gov/pubmed/25936916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.04.002
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