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Arginine-Rich Polyplexes for Gene Delivery to Neuronal Cells

Neuronal gene therapy potentially offers an effective therapeutic intervention to cure or slow the progression of neurological diseases. However, neuronal cells are difficult to transfect with nonviral vectors, and in vivo their transport across the blood-brain barrier (BBB) is inefficient. We synth...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Morris, Viola B., Labhasetwar, Vinod
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458175/
https://ncbi.nlm.nih.gov/pubmed/26000961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.04.052
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