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Co-delivery of DNA and siRNA via Arginine-Rich PEI-based Polyplexes

In this study, we formulated polyplexes with different compositions for co-delivery of DNA and small-interfering RNA (siRNA). Since DNA and siRNA have distinctive and complementary morphological characteristics (DNA is long and winding and siRNA is short and rigid), we hypothesized that their co-del...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Pharm
Hauptverfasser: Shan, Lu, Morris, Viola B, Labhasetwar, Vinod
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314506/
https://ncbi.nlm.nih.gov/pubmed/25591125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp5006883
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