Structural Bases for the Regulation of CO Binding in the Archaeal Protoglobin from Methanosarcina acetivorans

Studies of CO ligand binding revealed that two protein states with different ligand affinities exist in the protoglobin from Methanosarcina acetivorans (in MaPgb*, residue Cys(E20)101 was mutated to Ser). The switch between the two states occurs upon the ligation of MaPgb*. In this work, site-direct...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Tilleman, Lesley, Abbruzzetti, Stefania, Ciaccio, Chiara, De Sanctis, Giampiero, Nardini, Marco, Pesce, Alessandra, Desmet, Filip, Moens, Luc, Van Doorslaer, Sabine, Bruno, Stefano, Bolognesi, Martino, Ascenzi, Paolo, Coletta, Massimo, Viappiani, Cristiano, Dewilde, Sylvia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457829/
https://ncbi.nlm.nih.gov/pubmed/26047471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125959
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