Structural Bases for the Regulation of CO Binding in the Archaeal Protoglobin from Methanosarcina acetivorans

Studies of CO ligand binding revealed that two protein states with different ligand affinities exist in the protoglobin from Methanosarcina acetivorans (in MaPgb*, residue Cys(E20)101 was mutated to Ser). The switch between the two states occurs upon the ligation of MaPgb*. In this work, site-direct...

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Udgivet i:PLoS One
Main Authors: Tilleman, Lesley, Abbruzzetti, Stefania, Ciaccio, Chiara, De Sanctis, Giampiero, Nardini, Marco, Pesce, Alessandra, Desmet, Filip, Moens, Luc, Van Doorslaer, Sabine, Bruno, Stefano, Bolognesi, Martino, Ascenzi, Paolo, Coletta, Massimo, Viappiani, Cristiano, Dewilde, Sylvia
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457829/
https://ncbi.nlm.nih.gov/pubmed/26047471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125959
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