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Liposomal Formulation Decreases Toxicity of Amphotericin B In Vitro and In Vivo

BACKGROUND: Liposomal amphotericin B is locally delivered to treat fungal orthopaedic infections but little is known about local tissue toxicity, if any, that might be associated with local delivery. QUESTIONS/PURPOSES: (1) Is liposomal amphotericin B cytotoxic in vitro? (2) Is locally delivered lip...

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Publicado en:Clin Orthop Relat Res
Autores principales: Roberts, Justin, Bingham, Josh, McLaren, Alex C., McLemore, Ryan
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457755/
https://ncbi.nlm.nih.gov/pubmed/25804880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-015-4232-y
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