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Liposomal Formulation Increases Local Delivery of Amphotericin from Bone Cement: A Pilot Study

BACKGROUND: Amphotericin is a highly toxic hydrophobic antifungal. Delivery of amphotericin from antifungal-loaded bone cement (ALBC) is much lower than would be expected for an equivalent load of water-soluble antibacterials. Lipid formulations have been developed to decrease amphotericin toxicity....

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Hlavní autoři: Cunningham, Brian, McLaren, Alex C., Pauken, Christine, McLemore, Ryan
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442012/
https://ncbi.nlm.nih.gov/pubmed/22467417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-012-2317-4
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