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Amphotericin B Is Cytotoxic at Locally Delivered Concentrations

BACKGROUND: Orthopaedic fungal infections are commonly treated with systemic amphotericin, which has a narrow therapeutic index and is associated with systemic toxicities. Local delivery of amphotericin has been described yet is poorly understood. As with bacterial infections, fungal infections are...

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Bibliographic Details
Main Authors: Harmsen, Samuel, McLaren, Alex C., Pauken, Christine, McLemore, Ryan
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183219/
https://ncbi.nlm.nih.gov/pubmed/21484472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-011-1890-2
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