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Distribution of Locally Delivered Antimicrobials Is Limited by Cortical Bone: A Pilot Study

BACKGROUND: Local delivery is required to achieve the high antimicrobial concentrations needed to treat biofilm-forming infections. The delivery site is commonly either in the intramedullary canal or at the periosteal surface. It is unknown whether locally delivered antimicrobials are transported tr...

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Detalhes bibliográficos
Main Authors: Odgers, Ryan, Jarbo, Keith, McLaren, Alex, McLemore, Ryan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773106/
https://ncbi.nlm.nih.gov/pubmed/23430721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-013-2853-6
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