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Liposomal Formulation Increases Local Delivery of Amphotericin from Bone Cement: A Pilot Study
BACKGROUND: Amphotericin is a highly toxic hydrophobic antifungal. Delivery of amphotericin from antifungal-loaded bone cement (ALBC) is much lower than would be expected for an equivalent load of water-soluble antibacterials. Lipid formulations have been developed to decrease amphotericin toxicity....
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer-Verlag
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3442012/ https://ncbi.nlm.nih.gov/pubmed/22467417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-012-2317-4 |
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