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Effects of High Fat Feeding and Diabetes on Regression of Atherosclerosis Induced by Low-Density Lipoprotein Receptor Gene Therapy in LDL Receptor-Deficient Mice
We tested whether a high fat diet (HFD) containing the inflammatory dietary fatty acid palmitate or insulin deficient diabetes altered the remodeling of atherosclerotic plaques in LDL receptor knockout (Ldlr(-/-)) mice. Cholesterol reduction was achieved by using a helper-dependent adenovirus (HDAd)...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457481/ https://ncbi.nlm.nih.gov/pubmed/26046657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128996 |
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