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Gene Therapy Targeting LDL Cholesterol but not HDL Cholesterol Induces Regression of Advanced Atherosclerosis in a Mouse Model of Familial Hypercholesterolemia

A reduction in low density lipoprotein (LDL) cholesterol or an increase in high density lipoprotein (HDL) cholesterol can reduce the risk of development of atherosclerosis through overlapping or independent mechanisms. However, the clinical outcome of combined therapy remains in debate. In this stud...

詳細記述

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書誌詳細
主要な著者: Li, Rongying, Chao, Hsu, Ko, Kerry W.S., Cormier, Shelley, Dieker, Carrie, Nour, Elie A., Wang, Shining, Chan, Lawrence, Oka, Kazuhiro
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480198/
https://ncbi.nlm.nih.gov/pubmed/23106034
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