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Gene Therapy Targeting LDL Cholesterol but not HDL Cholesterol Induces Regression of Advanced Atherosclerosis in a Mouse Model of Familial Hypercholesterolemia

A reduction in low density lipoprotein (LDL) cholesterol or an increase in high density lipoprotein (HDL) cholesterol can reduce the risk of development of atherosclerosis through overlapping or independent mechanisms. However, the clinical outcome of combined therapy remains in debate. In this stud...

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Autors principals: Li, Rongying, Chao, Hsu, Ko, Kerry W.S., Cormier, Shelley, Dieker, Carrie, Nour, Elie A., Wang, Shining, Chan, Lawrence, Oka, Kazuhiro
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480198/
https://ncbi.nlm.nih.gov/pubmed/23106034
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