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Structure–activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL)
Adipose triglyceride lipase (ATGL) catalyzes the degradation of cellular triacylglycerol stores and strongly determines the concentration of circulating fatty acids (FAs). High serum FA levels are causally linked to the development of insulin resistance and impaired glucose tolerance, which eventual...
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| 發表在: | Bioorg Med Chem |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier Science
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457358/ https://ncbi.nlm.nih.gov/pubmed/25778769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.02.051 |
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