Structure–activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL)

Adipose triglyceride lipase (ATGL) catalyzes the degradation of cellular triacylglycerol stores and strongly determines the concentration of circulating fatty acids (FAs). High serum FA levels are causally linked to the development of insulin resistance and impaired glucose tolerance, which eventual...

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Bibliografiset tiedot
Julkaisussa:Bioorg Med Chem
Päätekijät: Mayer, Nicole, Schweiger, Martina, Melcher, Michaela-Christina, Fledelius, Christian, Zechner, Rudolf, Zimmermann, Robert, Breinbauer, Rolf
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier Science 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457358/
https://ncbi.nlm.nih.gov/pubmed/25778769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.02.051
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