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Targeting protein-protein interactions in hematologic malignancies: still a challenge or a great opportunity for future therapies?

Over the past several years, there has been an increasing research effort focused on inhibition of protein-protein interactions (PPIs) to develop novel therapeutic approaches for cancer, including hematologic malignancies. These efforts have led to development of small molecule inhibitors of PPIs, s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Immunol Rev
Hauptverfasser: Cierpicki, Tomasz, Grembecka, Jolanta
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457300/
https://ncbi.nlm.nih.gov/pubmed/25510283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12244
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