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Suppression of Th2 cell development by Notch ligands Delta 1 and 4()
Notch signaling plays important roles in Th cell activation. Here, we show that in response to TLR ligation, dendritic cells upregulate expression of Notch ligands Delta1 and Delta4 via a MyD88-dependent pathway. Expression of Delta1 or Delta4 by dendritic cells enhanced their ability to activate na...
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| Publicado no: | J Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457297/ https://ncbi.nlm.nih.gov/pubmed/18209061 |
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