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Traction forces mediated by integrin signaling are necessary for definitive endoderm specification

Pluripotent embryonic stem cells (ESCs) exert low-traction forces on their niche in vitro whereas specification to definitive endoderm in vivo coincides with force-mediated motility, suggesting a differentiation-mediated switch. However, the onset of contractility and extent to which force-mediated...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Sci
Prif Awduron: Taylor-Weiner, Hermes, Ravi, Neeraja, Engler, Adam J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457159/
https://ncbi.nlm.nih.gov/pubmed/25908864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.166157
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