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Defined Extracellular Matrix Components are Necessary for Definitive Endoderm Induction

Differentiation methods often rely exclusively on growth factors to direct mouse embryonic stem cell (ESC) fate, but the niche also contains fibrillar extracellular matrix (ECM) proteins, including fibronectin (FN) and laminin, which could also direct cell fate. Soluble differentiation factors are k...

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Detalhes bibliográficos
Main Authors: Taylor-Weiner, Hermes, Schwarzbauer, Jean E., Engler, Adam J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812380/
https://ncbi.nlm.nih.gov/pubmed/23766144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1453
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