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A minimally invasive, lentiviral based method for the rapid and sustained genetic manipulation of renal tubules
The accelerated discovery of disease-related genes emerging from genomic studies has strained the capacity of traditional genetically engineered mouse models (GEMMs) to provide in-vivo validation. Direct, somatic, genetic engineering approaches allow for accelerated and flexible genetic manipulation...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457145/ https://ncbi.nlm.nih.gov/pubmed/26046460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11061 |
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