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Identification of the First Sodium Binding Site of the Phosphate Cotransporter NaPi-IIa (SLC34A1)
Transporters of the SLC34 family (NaPi-IIa,b,c) catalyze uptake of inorganic phosphate (P(i)) in renal and intestinal epithelia. The transport cycle requires three Na(+) ions and one divalent P(i) to bind before a conformational change enables translocation, intracellular release of the substrates,...
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| Pubblicato in: | Biophys J |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457043/ https://ncbi.nlm.nih.gov/pubmed/25992725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.03.054 |
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