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Animal Models of Interferon Signature Positive Lupus
Human lupus is strongly associated with a gene expression signature characterized by over-expression of Type I interferon-regulated genes. A strong interferon signature generally is not seen in the standard mouse models of lupus, despite considerable evidence for the involvement of toll-like recepto...
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| Veröffentlicht in: | Front Immunol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456949/ https://ncbi.nlm.nih.gov/pubmed/26097482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00291 |
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