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Ten modifiers of BRCA1 penetrance validated in a Norwegian series
BACKGROUND: Common genetic variants have been shown to modify BRCA1 penetrance. The aim of this study was to validate these reports in a special cohort of Norwegian BRCA1 mutation carriers that were selected for their extreme age of onset of disease. METHODS: The ten variants rs13387042, rs3803662,...
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| Yayımlandı: | Hered Cancer Clin Pract |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BioMed Central
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456774/ https://ncbi.nlm.nih.gov/pubmed/26052370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13053-015-0035-0 |
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