Neurofilament light chain: A prognostic biomarker in amyotrophic lateral sclerosis

OBJECTIVE: To test blood and CSF neurofilament light chain (NfL) levels in relation to disease progression and survival in amyotrophic lateral sclerosis (ALS). METHODS: Using an electrochemiluminescence immunoassay, NfL levels were measured in samples from 2 cohorts of patients with sporadic ALS and...

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Veröffentlicht in:Neurology
Hauptverfasser: Lu, Ching-Hua, Macdonald-Wallis, Corrie, Gray, Elizabeth, Pearce, Neil, Petzold, Axel, Norgren, Niklas, Giovannoni, Gavin, Fratta, Pietro, Sidle, Katie, Fish, Mark, Orrell, Richard, Howard, Robin, Talbot, Kevin, Greensmith, Linda, Kuhle, Jens, Turner, Martin R., Malaspina, Andrea
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456658/
https://ncbi.nlm.nih.gov/pubmed/25934855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001642
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