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Piezo1 links mechanical forces to red blood cell volume

Red blood cells (RBCs) experience significant mechanical forces while recirculating, but the consequences of these forces are not fully understood. Recent work has shown that gain-of-function mutations in mechanically activated Piezo1 cation channels are associated with the dehydrating RBC disease x...

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Foilsithe in:eLife
Main Authors: Cahalan, Stuart M, Lukacs, Viktor, Ranade, Sanjeev S, Chien, Shu, Bandell, Michael, Patapoutian, Ardem
Formáid: Artigo
Teanga:Inglês
Foilsithe: eLife Sciences Publications, Ltd 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456639/
https://ncbi.nlm.nih.gov/pubmed/26001274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07370
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