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Piezo1 links mechanical forces to red blood cell volume

Red blood cells (RBCs) experience significant mechanical forces while recirculating, but the consequences of these forces are not fully understood. Recent work has shown that gain-of-function mutations in mechanically activated Piezo1 cation channels are associated with the dehydrating RBC disease x...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Cahalan, Stuart M, Lukacs, Viktor, Ranade, Sanjeev S, Chien, Shu, Bandell, Michael, Patapoutian, Ardem
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456639/
https://ncbi.nlm.nih.gov/pubmed/26001274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07370
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