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Piezo1 links mechanical forces to red blood cell volume

Red blood cells (RBCs) experience significant mechanical forces while recirculating, but the consequences of these forces are not fully understood. Recent work has shown that gain-of-function mutations in mechanically activated Piezo1 cation channels are associated with the dehydrating RBC disease x...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Cahalan, Stuart M, Lukacs, Viktor, Ranade, Sanjeev S, Chien, Shu, Bandell, Michael, Patapoutian, Ardem
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456639/
https://ncbi.nlm.nih.gov/pubmed/26001274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07370
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