Overexpression of NF90-NF45 Represses Myogenic MicroRNA Biogenesis, Resulting in Development of Skeletal Muscle Atrophy and Centronuclear Muscle Fibers

MicroRNAs (miRNAs) are involved in the progression and suppression of various diseases through translational inhibition of target mRNAs. Therefore, the alteration of miRNA biogenesis induces several diseases. The nuclear factor 90 (NF90)-NF45 complex is known as a negative regulator in miRNA biogene...

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Gepubliceerd in:Mol Cell Biol
Hoofdauteurs: Todaka, Hiroshi, Higuchi, Takuma, Yagyu, Ken-ichi, Sugiyama, Yasunori, Yamaguchi, Fumika, Morisawa, Keiko, Ono, Masafumi, Fukushima, Atsuki, Tsuda, Masayuki, Taniguchi, Taketoshi, Sakamoto, Shuji
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456438/
https://ncbi.nlm.nih.gov/pubmed/25918244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01297-14
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