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Dishevelled-2 regulates cocaine-induced structural plasticity and Rac1 activity in the nucleus accumbens

Chronic cocaine exposure increases the density of dendritic spines on medium spiny neurons (MSNs), the predominant neuronal cell type of the nucleus accumbens (NAc), a key brain reward region. We recently showed that suppression of Rac1, a small GTPase, is a critical mediator of this structural plas...

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Библиографические подробности
Опубликовано в: :Neurosci Lett
Главные авторы: Dias, Caroline, Dietz, David, Mazei-Robison, Michelle, Sun, Haosheng, Damez-Werno, Diane, Ferguson, Deveroux, Wilkinson, Matthew, Magida, Jane, Gao, Virginia, Neve, Rachael, Nestler, Eric J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456346/
https://ncbi.nlm.nih.gov/pubmed/25957559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2015.05.003
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