A Novel Role of the WNT-Dishevelled-GSK3β Signaling Cascade in the Mouse Nucleus Accumbens in a Social Defeat Model of Depression

Based on earlier gene expression and chromatin array data, we identified the protein, dishevelled (DVL)-2, as being regulated in the nucleus accumbens (NAc), a key brain reward region, in the mouse social defeat model of depression. Here, we validate these findings by showing that DVL2 mRNA and prot...

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Autors principals: Wilkinson, Matthew B., Dias, Caroline, Magida, Jane, Mazei-Robison, Michelle, Lobo, MaryKay, Kennedy, Pamela, Dietz, David, Covington, Herbert, Russo, Scott, Neve, Rachael, Ghose, Subroto, Tamminga, Carol, Nestler, Eric J.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133937/
https://ncbi.nlm.nih.gov/pubmed/21697359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0039-11.2011
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