Fluoxetine Epigenetically Alters the CaMKIIα Promoter in Nucleus Accumbens to Regulate ΔFosB Binding and Antidepressant Effects

Chronic social defeat stress in mice produces a susceptible phenotype characterized by several behavioral abnormalities consistent with human depression that are reversed by chronic but not acute exposure to antidepressant medications. Recent work in addiction models demonstrates that the transcript...

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Detalhes bibliográficos
Main Authors: Robison, A J, Vialou, Vincent, Sun, Hao-Sheng, Labonte, Benoit, A Golden, Sam, Dias, Caroline, Turecki, Gustavo, Tamminga, Carol, Russo, Scott, Mazei-Robison, Michelle, Nestler, Eric J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957112/
https://ncbi.nlm.nih.gov/pubmed/24240473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.319
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