SIRT1-FOXO3a Regulate Cocaine Actions in the Nucleus Accumbens

Previous studies have shown that chronic cocaine administration induces SIRT1, a Class III histone deacetylase, in the nucleus accumbens (NAc), a key brain reward region, and that such induction influences the gene regulation and place conditioning effects of cocaine. To determine the mechanisms by...

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Vydáno v:J Neurosci
Hlavní autoři: Ferguson, Deveroux, Shao, Ningyi, Heller, Elizabeth, Feng, Jian, Neve, Rachael, Kim, Hee-Dae, Call, Tanessa, Magazu, Samantha, Shen, Li, Nestler, Eric J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331629/
https://ncbi.nlm.nih.gov/pubmed/25698746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4012-14.2015
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