Učitavanje...
PTPROt-mediated regulation of p53/Foxm1 suppresses leukemic phenotype in a CLL mouse model
The gene encoding PTPROt is methylated and suppressed in Chronic Lymphocytc Leukemia. PTPROt exhibits in vitro tumor suppressor characteristics through the regulation of B-cell receptor signaling. Here, we generated transgenic (Tg) mice with B-cell specific expression of PTPROt. While lymphocyte dev...
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| Izdano u: | Leukemia |
|---|---|
| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456291/ https://ncbi.nlm.nih.gov/pubmed/25482129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2014.341 |
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