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Notch reporter activity in breast cancer cell lines identifies a subset of cells with stem cell activity

Developmental pathways such as Notch play a pivotal role in tissue specific stem cell self-renewal as well as in tumor development. However, the role of Notch signaling in breast cancer stem cells (CSC) remains to be determined. We utilized a lentiviral Notch reporter system to identify a subset of...

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發表在:Mol Cancer Ther
Main Authors: D’Angelo, Rosemarie C., Ouzounova, Maria, Davis, April, Choi, Daejin, Tchuenkam, Stevie M., Kim, Gwangil, Luther, Tahra, Quraishi, Ahmed A., Senbabaoglu, Yasin, Conley, Sarah J., Clouthier, Shawn G., Hassan, Khaled A., Wicha, Max S., Korkaya, Hasan
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456218/
https://ncbi.nlm.nih.gov/pubmed/25673823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0228
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