DNA double helix promotes a linkage isomerization reaction in trans-diamminedichloroplatinum(II)-modified DNA.

In the reaction between trans-diamminedichloroplatinum(II) and a single-stranded pyrimidin-rich oligodeoxyribonucleotide (22-mer) containing the central sequence TGAGT, the 1,3-trans-[Pt(NH3)2[d(GAG)]] cross-link is formed. The 1,3-intrastrand cross-link is inert within the single-stranded oligonucl...

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Julkaisussa:	Proc Natl Acad Sci U S A
Päätekijät:	Dalbiès, R, Payet, D, Leng, M
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	National Academy of Sciences 1994
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44562/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8058771/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.17.8147
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