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β-cell Failure as a Complication of Diabetes
Type 2 diabetes mellitus is a complex disease characterized by β-cell failure in the setting of insulin resistance. In early stages of the disease, pancreatic β-cells adapt to insulin resistance by increasing mass and function. As nutrient excess persists, hyperglycemia and elevated free fatty acids...
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| Publicado en: | Rev Endocr Metab Disord |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456188/ https://ncbi.nlm.nih.gov/pubmed/18777097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11154-008-9101-5 |
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