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Enantioselective Rh-Catalyzed Hydroacylation of Olefins: From Serendipitous Discovery to Rational Design

Rh-catalysed hydroacylation allows the construction of chiral ketones from olefins and aldehydes. Since James' and Young's serendipitous discovery of the enantioselective 4-pentenal cyclisation, both intra and intermolecular variants have emerged that enable broader applications.

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Dettagli Bibliografici
Pubblicato in:Chem Commun (Camb)
Autori principali: Murphy, Stephen K., Dong, Vy M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456096/
https://ncbi.nlm.nih.gov/pubmed/25277153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc02276a
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