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Decoding Split and Pool Combinatorial Libraries with Electron Transfer Dissociation Tandem Mass Spectrometry

Screening of bead-based split and pool combinatorial chemistry libraries is a powerful approach to aid the discovery of new chemical compounds able to interact with, and modulate the activities of, protein targets of interest. Split and pool synthesis provides for large and well diversified chemical...

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Détails bibliographiques
Publié dans:J Am Soc Mass Spectrom
Auteurs principaux: Sarkar, Mohosin, Pascal, Bruce D., Steckler, Caitlin, Aquino, Claudio, Micalizio, Glenn C., Kodadek, Thomas, Chalmers, Michael J.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455952/
https://ncbi.nlm.nih.gov/pubmed/23636859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-013-0633-x
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