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Decoding Split and Pool Combinatorial Libraries with Electron Transfer Dissociation Tandem Mass Spectrometry

Screening of bead-based split and pool combinatorial chemistry libraries is a powerful approach to aid the discovery of new chemical compounds able to interact with, and modulate the activities of, protein targets of interest. Split and pool synthesis provides for large and well diversified chemical...

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Bibliografiske detaljer
Udgivet i:J Am Soc Mass Spectrom
Main Authors: Sarkar, Mohosin, Pascal, Bruce D., Steckler, Caitlin, Aquino, Claudio, Micalizio, Glenn C., Kodadek, Thomas, Chalmers, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455952/
https://ncbi.nlm.nih.gov/pubmed/23636859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-013-0633-x
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