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Quantitative Microarray Analysis of Intact Glycolipid–CD1d Interaction and Correlation with Cell-Based Cytokine Production
The protein CD1d binds self and foreign glycolipids for presentation to CD1-restricted T cells by means of TCR recognition and activates T(H)1 and T(H)2 chemokine release. In this study, a variety of glycolipid ligands were attached to a microarray surface and their binding with dimeric CD1d was inv...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4455950/ https://ncbi.nlm.nih.gov/pubmed/18712867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8012787 |
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