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mTOR, a new potential target for chronic pain and opioid-induced tolerance and hyperalgesia

Chronic pain is a major public health problem with limited treatment options. Opioids remain a routine treatment for chronic pain, but extended exposure to opioid therapy can produce opioid tolerance and hyperalgesia. Although the mechanisms underlying chronic pain, opioid-induced tolerance, and opi...

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Détails bibliographiques
Publié dans:Mol Pain
Auteurs principaux: Lutz, Brianna Marie, Nia, Sam, Xiong, Ming, Tao, Yuan-Xiang, Bekker, Alex
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455918/
https://ncbi.nlm.nih.gov/pubmed/26024835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12990-015-0030-5
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