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mTOR, a new potential target for chronic pain and opioid-induced tolerance and hyperalgesia
Chronic pain is a major public health problem with limited treatment options. Opioids remain a routine treatment for chronic pain, but extended exposure to opioid therapy can produce opioid tolerance and hyperalgesia. Although the mechanisms underlying chronic pain, opioid-induced tolerance, and opi...
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Publicado no: | Mol Pain |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4455918/ https://ncbi.nlm.nih.gov/pubmed/26024835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12990-015-0030-5 |
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